1 Step: Questionnaire Review (Preparation)

1 Step: Questionnaire Review (Preparation)
(depending on variant of medication)

Patient should stop taking immunomodulating drugs in 3-6 months before admission

You should treat all types of infections before AHSCT (urine tract infection, oral cavity, dental etc.)

You should keep using all symptomatic medications (pain medicine, Fampyra, LDN, antidepressants) or medications for treatment comorbidities (high blood pressure, anticoagulants, diabetes treatment etc.).

If you take steroids (prednisolone, dexamethasone, methylprednisolone) keep using it.

In spite of low risk of infertility (3-5% after lymphoablative protocol), we recommend to preserve sperm or embryo before AHSCT.
medications cancellation list
Medications cancellation list (6 months before AHSCT)

  1. Teriflunomide (Aubagio)
  2. Lemtrada (Alemtuzumab)
  3. Novantrone (Mitoxantrone)
  4. Rituximab (Mabthera)
  5. Ocrelizumab (Ocrevus)
  6. Daclizumab (Zinbryta)
  7. Azatioprin (Imuran)
  8. Methotrexate
  9. Cyclophosphamide (Cytoxan)
  10. Cladribine (Leustat)

medications cancellation list 2
Medications cancellation list (3 months before AHSCT)

  1. Natalizumab (Tysabri)
  2. Fingolimod (Gilenya)
  3. Dimethyl fumarate (Tecfidera)
  4. Interferon beta-1a (Avonex) (Rebif)
  5. Interferon beta-1b (Betaseron, Extavia
  6. Glatiramer acetate (Copaxone)
  7. Laquinimod (Nerventra)
  8. Ibudilast (MN-166)
  9. Mycophenolata Mofetil (CellCept)